VISDB Viral Integration Site DataBase

VIS ID

TVIS10009914

Fusion event

HBV-CDH8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2715

Orient

+

Integrated sequence

AGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACA| |TCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGT

Chromosome

chr16

Cytoband

q21

Reference genome

Start

End

62031062/61997158 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4469 ; hsa-mir-6832-3p ; hsa-mir-6741-3p ; hsa-mir-6867-3p ; hsa-mir-6817-3p ; hsa-mir-6845-3p ; hsa-mir-7113-3p ; hsa-mir-3667-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-642a-5p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-7110-3p ; hsa-mir-1304-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183

Nearest miRNA

hsa-mir-1225/Upstream/4224806; hsa-mir-11401/Downstream/5205163;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/2241990, chr16-CpG: 117/Downstream/38059

Upstream sequence

GTTTTTTTAAAAAAGAATAATTCTTCTCCTTTATCCTAAGATTCAGATTTTCTCTAAAAAAGTCATAAAGTCATAATTTTAATGTTATTTCCAAGCCACC

Downstream sequence

TTAACTTAAAGTCTCTCAGAGTCCACTTTGCTGATGTGCCAGGAATTCTCACAATATTCCGCAATCCTGCCTTATGGTACACTGTTTGAAATAAAATAAA