VISDB Viral Integration Site DataBase

VIS ID

TVIS10009915

Fusion event

HBV-SLC12A4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1527

Orient

+

Integrated sequence

TACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGC| |GCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAAC

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

67990005/67956102 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-155-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-let-7e-5p

Nearest miRNA

hsa-mir-1225/Upstream/753707; hsa-mir-11401/Downstream/277324;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/19587, chr16-CpG: 79/Downstream/12074

Upstream sequence

cccatctctactaaaaatacaaaaattagctgagcatggtggtgcatgtctgtaatcccagctactcgggcggctgaggcaggagaatcgcttgaacctg

Downstream sequence

ggaggtggagattgcagtgagctgagatcgtgccactgcactccagcctgggcgacacactccgtctcaaaataaataaataaataaataaaCGaaaagt