Basic Information
VIS ID
TVIS10009923
Fusion event
HBV-SNHG20 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr17
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
75089289/77093207 (Hg38)
End
75089289/77093207 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SNHG20
Nearest miRNA
hsa-mir-10226/Upstream/3710; hsa-mir-1250/Downstream/303777;
Nearest TSS
ENST00000595228/Upstream/4052; ENST00000588880/Downstream/34666;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/4204, chr17-CpG: 146/Downstream/47036
Upstream sequence
CAGGGTACCTCCCATGTCATGTTCTAGGTGGAAGGTGGATTTTAGATTTTAGAGAGTATCTCATGGAGCTCACAGTTTTAAATATTCAGACTTGGTAAAG
Downstream sequence
TAGAATAAGAACTGATGCATATACTTTTCTTTGCAGGTCAGTTTCTGGAAGACTTGTGTGTGTGATGAATGAATATCTGGTTTTGTCTCTGCTGGGCCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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