VISDB Viral Integration Site DataBase

VIS ID

TVIS10009938

Fusion event

HBV-FRZB integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

697

Orient

-

Integrated sequence

ACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTC| |AGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACC

Chromosome

chr2

Cytoband

q32.1

Reference genome

Start

End

183725493/182860765 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-744-5p ; hsa-mir-451a ; hsa-mir-125b-1-3p

Nearest miRNA

hsa-mir-10b/Upstream/1555113; hsa-mir-1244-1/Downstream/1518210;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/144290, chr2-CpG: 38/Downstream/5315

Upstream sequence

agaccagcctggccaacatggcgaaaacccatctctaacagaaatacaaaaattagctgggcgtggtggcatgcacctgtagtcccagctactcaggagg

Downstream sequence

ctgagacaggagaattgcttgaaccttggaggcagaggttgcagtgagcagagatcacgccactgcactccagtctgagtgacagagcgagactgtctca