Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009939
Fusion event
HBV-ZNF804A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1803
Orient
-
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |CGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
End
185568308/184703581 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/324537; hsa-mir-1244-1/Downstream/3593911;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/104719, chr2-CpG: 53/Downstream/1035084
Upstream sequence
catgagatcaggagatcgagaccacggtgaaaccccgtctctactaaaacacaaaaaaattagccgggcgtggtggcgggcgcctgtagtctcagctact
Downstream sequence
ggggaggctgaggcaggagaatggcgtgaacccaggaggtggagcttgcagtgagccgagattgcgccactgcactccagcctgggcgacagagcaagac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.