VISDB Viral Integration Site DataBase

VIS ID

TVIS10009940

Fusion event

HBV-METTL21A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr2

Cytoband

q33.3

Reference genome

Start

End

208476662/207611938 (Hg38)

Orient

+

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-4646-3p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-6831-3p ; hsa-mir-345-5p ; hsa-mir-330-3p ; hsa-mir-3908 ; hsa-mir-6835-3p ; hsa-mir-3120-3p ; hsa-mir-548c-3p ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-4749-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-1225-3p ; hsa-mir-6887-3p ; hsa-mir-1470 ; hsa-mir-6769a-3p ; hsa-mir-5089-5p ; hsa-mir-6869-5p ; hsa-mir-1200 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-566 ; hsa-mir-6720-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6730-3p ; hsa-mir-3653-5p ; hsa-mir-6078 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-4707-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4796-3p ; hsa-mir-1180-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-3943 ; hsa-mir-639 ; hsa-mir-7977 ; hsa-mir-4772-3p ; hsa-mir-1306-5p ; hsa-mir-6746-3p ; hsa-mir-6776-3p

Nearest miRNA

hsa-mir-10b/Upstream/342514; hsa-mir-1244-1/Downstream/142869;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/81285, chr2-CpG: 157/Downstream/12766

Upstream sequence

atcaccactccctaatcttaagtacccagggacacaaacactgcggaaggccaaggccgcagggtcctctgcctaggaaaaccagagacctttgttcact

Downstream sequence

tgtttatctgctgaccttccctccactattgtcctatgaccctgccaaatccccctctgcgagaaacacccaagaatgatcaataaaaaaaaaataaaTT