VISDB Viral Integration Site DataBase

VIS ID

TVIS10009963

Fusion event

HBV-ZHX3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1833

Orient

+

Integrated sequence

GGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTC| |TGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAG

Chromosome

chr20

Cytoband

q12

Reference genome

Start

End

39871848/41243208 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-877-3p ; hsa-mir-3171 ; hsa-mir-4778-5p ; hsa-mir-100-3p ; hsa-mir-548e-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-1183 ; hsa-mir-4793-3p ; hsa-mir-3130-3p ; hsa-mir-6749-3p ; hsa-mir-6826-3p ; hsa-mir-3117-5p ; hsa-mir-150-5p ; hsa-mir-6887-3p ; hsa-mir-6795-3p ; hsa-mir-186-3p ; hsa-mir-483-3p ; hsa-mir-425-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/74130; hsa-mir-1-1/Downstream/3164912;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/105016, chr20-CpG: 121/Downstream/73746

Upstream sequence

CCAGTGCTCCAAGAGAGGGAGAAATACTTCCTCTATAAAATAATGGGGAGTCAGAGGCATATGGGATTTCCCTTTGCTTCCATGAAATTAGGAGAAAGCA

Downstream sequence

CCAACACTTTCTAGTAATTCCACAGTGAATAGGATGTGCTACCAGCCCAGCATCAGTAGGGCTTCTCTTCATTCTCAAGAAGTGTAATTACCTGACGTGG