VISDB Viral Integration Site DataBase

VIS ID

TVIS10009974

Fusion event

HBV-SLC2A11 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1727

Orient

-

Integrated sequence

GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT

Chromosome

chr22

Cytoband

q11.23

Reference genome

Start

End

24198389/23856202 (Hg38)

Orient

+

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-let-7e-5p ; hsa-mir-3157-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4711-5p ; hsa-mir-4691-3p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-3606-3p ; hsa-mir-653-3p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-5189-3p ; hsa-mir-4742-3p ; hsa-mir-6890-3p ; hsa-mir-649 ; hsa-mir-129-5p ; hsa-mir-3529-5p ; hsa-mir-379-5p ; hsa-mir-4451 ; hsa-mir-4650-3p

Nearest miRNA

hsa-mir-1286/Upstream/969823; hsa-let-7a-3/Downstream/1599444;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/6404, chr22-CpG: 98/Downstream/669

Upstream sequence

atcaccactccctaatcttaagtacccagggacacaaacactgcggaaggccaaggccgcagggtcctctgcctaggaaaaccagagacctttgttcact

Downstream sequence

tgtttatctgctgaccttccctccactattgtcctatgaccctgccaaatccccctctgcgagaaacacccaagaatgatcaataaaaaaaaaataaata