Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009979
Fusion event
HBV-RPL23AP82 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
639
Orient
-
Integrated sequence
TCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTC| |CTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTA
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
Start
End
51224787/50786359 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-let-7a-3/Upstream/378835;
Nearest TSS
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/2470, None/Downstream
Upstream sequence
aggggttagggttagggtttagggttagggtttagggttaggggttggggttaggggttggttagggttaggggttaggggttagggttagggttagggt
Downstream sequence
taggattaggggttatggttagggttatggtACTGTAAATAATTTCACATTATTACTAATAATAAATTATTATTTGTATTACACTATTACATAATGTAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.