VISDB Viral Integration Site DataBase

VIS ID

TVIS10009984

Fusion event

HBV-ZMAT3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1835

Orient

-

Integrated sequence

GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCT

Chromosome

chr3

Cytoband

q26.32

Reference genome

Start

End

178739986/179022198 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-3613-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-4289 ; hsa-mir-8084 ; hsa-mir-4469 ; hsa-mir-361-5p ; hsa-mir-626 ; hsa-mir-512-3p ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-374b-3p ; hsa-mir-944 ; hsa-mir-578 ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-580-3p ; hsa-mir-526b-5p ; hsa-mir-3928-3p ; hsa-mir-539-5p ; hsa-mir-4766-5p ; hsa-mir-654-3p ; hsa-mir-409-3p ; hsa-mir-4282 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-130a-3p ; hsa-mir-451b ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-1468-3p ; hsa-mir-545-3p ; hsa-mir-4698 ; hsa-mir-646 ; hsa-mir-548p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-503-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548s ; hsa-mir-1178-3p ; hsa-mir-3926 ; hsa-mir-7158-5p ; hsa-mir-18b-3p ; hsa-mir-3190-5p ; hsa-mir-5009-3p ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-302f ; hsa-mir-374a-3p ; hsa-mir-1245b-3p ; hsa-mir-2115-3p ; hsa-mir-369-3p ; hsa-mir-5692a ; hsa-mir-3591-5p ; hsa-mir-7705 ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-591 ; hsa-mir-6513-3p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-33a-3p ; hsa-mir-2355-3p ; hsa-mir-676-3p ; hsa-mir-488-3p ; hsa-mir-6749-3p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-219a-2-3p ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-5089-5p ; hsa-mir-4665-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-4485-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-190a-3p ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-5011-5p ; hsa-mir-1277-5p

Nearest miRNA

hsa-let-7g/Upstream/2507047; hsa-mir-1224/Downstream/4864602;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/1824132, chr3-CpG: 63/Downstream/49319

Upstream sequence

cacatgcacacctatgtttattgtggcactattcacaatagcaaagacttgaaaccaacccaaatgtccatcaacaatagactggattaagaaaatgtgg

Downstream sequence

AAGGCCTGAAAAAACATCAAGCCCTTAAGTCGGCTGCTTTTTCTACGTATATAATGAAATTGTTAAGTGGAGAGAGCAAGGGGAACCCTTCTTATAAAAC