VISDB Viral Integration Site DataBase

VIS ID

TVIS10009986

Fusion event

HBV-SUSD5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2080

Orient

+

Integrated sequence

GTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTC| |TTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATAT

Chromosome

chr3

Cytoband

p22.3

Reference genome

Start

End

33246257/33204765 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-526b-5p ; hsa-mir-4459 ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-5584-3p ; hsa-mir-1273g-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-6875-3p ; hsa-mir-6794-3p ; hsa-mir-6867-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-483-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p

Nearest miRNA

hsa-mir-12127/Upstream/698376; hsa-let-7g/Downstream/2539711;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/90252, chr3-CpG: 103/Downstream/13662

Upstream sequence

ctatcaatcgtgcctacgtaacaggactccgatcaaaactgaatagtgagacatgggtgaatttccctggttggcaatgcttcacatttatgtcacacat

Downstream sequence

gcctcctgagtggctaggattacaggcatgcaccactacatctggctaCAGCCTGAGCTTTTTGAGATTTTAAAattttatataatttcaaagttacata