VISDB Viral Integration Site DataBase

VIS ID

TVIS10010016

Fusion event

HBV-AHRR integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1788

Orient

-

Integrated sequence

CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG| |GCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTG

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

360107/359992 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26a-5p ; hsa-mir-18a-5p ; hsa-mir-125b-5p

Nearest miRNA

hsa-mir-10397/Downstream/702904;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/581, chr5-CpG: 24/Downstream/10078

Nearest cancer related gene

AHRR(TSG, No orient, 0)

Upstream sequence

GAAAAGTTAACAAATTTTAGGGTATTGGCAAATTGTTCAGTAAAATTATGTTGATGATGTTAACAAGAATGTTAAAGAAAATTTTGCAGGTGATAACACA

Downstream sequence

GATGATCTTTttatggactggatgtttgtctcatcccttcacctattcatatagtgaaaccctaattcccagtgtggccgtatttgtaggtgggtccgct