VISDB Viral Integration Site DataBase

VIS ID

TVIS10010020

Fusion event

HBV-ARHGEF28 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1881

Orient

+

Integrated sequence

GCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTG| |TGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAG

Chromosome

chr5

Cytoband

q13.2

Reference genome

Start

End

73024169/73728344 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-19b-3p ; hsa-mir-203a-3p ; hsa-mir-4635 ; hsa-mir-302a-5p ; hsa-mir-7161-3p ; hsa-mir-338-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-1226-3p ; hsa-mir-634 ; hsa-mir-6771-3p

Nearest miRNA

hsa-mir-10397/Upstream/849681; hsa-mir-103a-1/Downstream/9111811;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/101642, chr5-CpG: 29/Downstream/181141

Upstream sequence

TTAAATTATTCCTTTTTATCTTCAATTGTTTATACAGGTTTAACGGCAACAATCTTAACTAACAACAAGTAATGCCCTGGCTATTTATTGTACCATCGCA

Downstream sequence

TCCCTTTGTTGTGCCCCTACAGACCTTCACTCAAATTCTTAGCCTTGCAAGTCTGAAAACAAGTTTTCTTTCAAGTCAGATGTGCTATCTAAATCAAGTG