Basic Information
VIS ID
TVIS10010021
Fusion event
HBV-LINC02144 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
256
Orient
-
Integrated sequence
ATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACT| |CGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCC
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
End
86979814/87683997 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/569043; hsa-mir-103a-1/Downstream/982856;
Nearby gene
CCNH(-270964) ; TMEM161B(+511209) ;
Upstream sequence
cctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacccta
Downstream sequence
TCACATCTCTCTCAATGTACCCAGTCCCTCATCATTCCAACTTCATCAGGGTCCTGGCAGCATTGTGTTATCTACTCAGTGGCTCACACCACTCTCTCTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate