VISDB Viral Integration Site DataBase

VIS ID

TVIS10010030

Fusion event

HBV-COG5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

780

Orient

-

Integrated sequence

ACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATC| |TTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTAT

Chromosome

chr7

Cytoband

q22.3

Reference genome

Start

End

107060867/107420422 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-3978 ; hsa-mir-4261 ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-610 ; hsa-mir-181a-2-3p ; hsa-mir-497-3p

Nearest miRNA

hsa-mir-10525/Upstream/4948891; hsa-mir-10399/Downstream/7232923;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/250538, chr7-CpG: 59/Downstream/143247

Upstream sequence

TGCCACCTCCATGCCACTGCCAGAGCTGGCCTAGCAAGATGTGCTCTCAGAATGGCCGGGCCCAAGAGATGAAGGAAAGGAGTGAAAGGGAAGTAGGACC

Downstream sequence

AAGGAGTTCAGGTATTACAGAAAACAAACACAGGTTAAAAtttgtttgtttgttttgagacggagtcttgctctgtcgctcaggctggagtgcagtggtg