VISDB Viral Integration Site DataBase

VIS ID

TVIS10010044

Fusion event

HBV-CDK14 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2702

Orient

+

Integrated sequence

CTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTT| |ATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAG

Chromosome

chr7

Cytoband

q21.13

Reference genome

Start

End

90655332/91026017 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-376c-3p ; hsa-mir-493-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4533 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6783-5p ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4428

Nearest miRNA

hsa-mir-10525/Upstream/15110748; hsa-mir-10399/Downstream/1177998;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/428967, chr7-CpG: 255/Downstream/238261

Nearest cancer related gene

CDK14(OG, No orient, 0)

Upstream sequence

ggccttttttttttttgagacaggatcttgctttgcccaggctggaatgcagtagtgcagttatagctcactgcagcctggacctcctgggctcaagcag

Downstream sequence

AAGTTACCTTTTTTTTTTTAGTGAACATAATCATTAGAAGACTTTGCACCTTGGTTGGGCTGTCCCTTTGCTCCTCTTTGTTGACAGGCAGTCTTCTAAG