VISDB Viral Integration Site DataBase

VIS ID

TVIS10010060

Fusion event

HBV-COL15A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2296

Orient

+

Integrated sequence

CAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTT| |ATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAG

Chromosome

chr9

Cytoband

q22.33

Reference genome

Start

End

101817306/99055024 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-29b-3p

Nearest miRNA

hsa-let-7a-1/Upstream/825807; hsa-mir-12126/Downstream/7545904;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/69223, chr9-CpG: 142/Downstream/49688

Upstream sequence

TCTGTGTGAGAGAGATTACTGAGCAATCACAATTGCCCACTAAGGATGGGACTTACCTGAAGTTAGAGTTCTATTCTTAATGCTAAAACAGGATAATCTC

Downstream sequence

GGTTGCCAACTTAGAGACTTTTATTTTAAAATTTCTGAAATTACAATCGTGAATTTTACGAAGCATTTCTTTTTCAGGTCCTCCACTTGATCTAGCTTAC