VISDB Viral Integration Site DataBase

VIS ID

TVIS10010070

Fusion event

HBV-BNC2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1805

Orient

-

Integrated sequence

TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG

Chromosome

chr9

Cytoband

p22.3

Reference genome

Start

End

16525679/16525681 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-629-3p ; hsa-mir-3973 ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-8064 ; hsa-mir-892a ; hsa-mir-297 ; hsa-mir-4666b ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-455-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4499 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-2278 ; hsa-mir-561-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-17-3p ; hsa-mir-545-5p ; hsa-mir-410-3p ; hsa-mir-6867-3p ; hsa-mir-516a-5p ; hsa-mir-4713-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6740-3p ; hsa-mir-942-5p ; hsa-mir-1264 ; hsa-mir-510-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4315 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3691-3p ; hsa-mir-3908 ; hsa-mir-568

Nearest miRNA

hsa-mir-101-2/Upstream/10517777; hsa-let-7a-1/Downstream/2047625;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/972345, chr9-CpG: 30/Downstream/201180

Upstream sequence

aaccctaaccctaaccctaacccaaccccaccccaaccccaaccccaacccaaccctaaccctaaccctaacccaaccctaaccctaaccctaacccaac

Downstream sequence

agctctttatgtgctgatatgaagttgtttacaagatatattattaagtgaaaaaggaaaagtgcagaataatgtGCTCACTATATTCCCCTTCACCATT