Basic Information
VIS ID
TVIS10010071
Fusion event
HBV-chr9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
788
Orient
-
Integrated sequence
CATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCC| |CTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATG
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
End
1656872/1656872 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1302-9/Upstream/1626591; hsa-let-7a-1/Downstream/3193425;
Nearby gene
DMRT2(-599318) ; SMARCA2(+358470) ;
Nearest cancer related gene
SMARCA2(TSG, +358470) ;
Upstream sequence
acacctggctaattttgtatttttagtagagacagggtttcaccatgttggtcaggctggtctcgaactcctgacctcaagtgatccacctgccttggcc
Downstream sequence
tttgtatccagaaactttactgaagtcatttatcagttctaggagccttatggcaggcagagtctttagaattttctaggtatagaatcacatcatcagt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate