Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010074
Fusion event
HBV-HRCT1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1222
Orient
-
Integrated sequence
TGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCAT| |GGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAAC
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
Start
End
35905762/35905765 (Hg38)
Orient
-
Location type
upstream
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-2/Upstream/172770; hsa-let-7a-1/Downstream/917774;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/76351, chr9-CpG: 25/Downstream/66381
Upstream sequence
ttttggaataggtgtggtgtggtgttgaaaaaaatgtgtattctgttgatttggggtggagagttctgtagatgtctattatgtctgcttggtgcagagc
Downstream sequence
ctttacgcatctcaactcctttagtcctcggaacaccctactgaggaaggaaccgttatcagccattttacagaagaggaaacaggacagagaggttaag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.