VISDB Viral Integration Site DataBase

VIS ID

TVIS10010082

Fusion event

HBV-NEXMIF integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1822

Orient

+

Integrated sequence

GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA

Chromosome

chrX

Cytoband

q13.3

Reference genome

Start

End

74005745/74785910 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-5580-3p ; hsa-mir-382-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-5011-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3133 ; hsa-mir-642a-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-216b-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-600 ; hsa-mir-6769a-3p ; hsa-mir-3943 ; hsa-mir-4323

Nearest miRNA

hsa-let-7f-2/Upstream/498553; hsa-mir-105-1/Downstream/2133363;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/171148, chrX-CpG: 128/Downstream/138107

Upstream sequence

gttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtga

Downstream sequence

TAGATAAGGTAATAGACAAAACTTATGAAATAAATCTGCTTTCATGAAATTTGGTGTTTATGAAATATATGTTTTATATTTTATAGAGAACACTAAAGCA