Basic Information
VIS ID
TVIS10010091
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
639
Orient
-
Integrated sequence
TCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTC| |CTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTA
Host Sequence
Chromosome
chrY
Cytoband
q12
Reference genome
GRCh37/hg19
Start
59363465/57217314 (Hg38)
End
59363465/57217314 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/43738048;
Nearest TSS
ENST00000430575/Upstream/31488824;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/13891, None/Downstream
Nearby gene
IL9R(-19977) ;
Upstream sequence
actcggagtgattcaattccattctattccttttaattccattccattccattccattccattccattccattccattccattccattccattccattct
Downstream sequence
tagggtgtggtgtgtgggtgtgtgtgggtgtggtgtgtgtgggtgtggtgtgtgggtgtgggtgtgggtgtgggtgtgtgggtgtggtgtgtgggtgtgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate