DZIP3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010093
Fusion event
HBV-DZIP3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|
Start
2950
Orient
-
Integrated sequence
TGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTT| |CAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGC
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
108405548/108686701 (Hg38)
End
108405548/108686701 (Hg38)
Orient
+
Location type
Intronic
Target gene
DZIP3
miRNAs that regulate target gene
hsa-mir-130b-5p ; hsa-mir-93-5p
Nearest miRNA
hsa-let-7g/Upstream/5162585; hsa-mir-12124/Downstream/916127;
Nearest TSS
ENST00000440867/Upstream/83850; ENST00000478830/Downstream/70314;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/96944, chr3-CpG: 28/Downstream/431247
Upstream sequence
ttatagtattctctgatggtagtttgtatttctgtgggatcggtggtgatatcccctttatcatttgatattgtgtctatatgattcttctctcttttct
Downstream sequence
TTCCTTACCTTGACCTTGGTAAGGAAAAAGAAATTTACCAAGAAGAGACAGTGTTCAATGGTGAACCTCTTCATTAAAAAGTTACTTGTCTTAAATCATG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate