VISDB Viral Integration Site DataBase

VIS ID

TVIS10010102

Fusion event

HBV-SMG5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1998

Orient

+

Integrated sequence

GGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGAT| |ACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAA

Chromosome

chr1

Cytoband

q22

Reference genome

Start

End

156223420/156253629 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-708-5p ; hsa-mir-130b-5p ; hsa-mir-106b-3p ; hsa-mir-193b-3p ; hsa-mir-331-3p

Nearest miRNA

hsa-mir-101-1/Upstream/302293; hsa-mir-1182/Downstream/166712;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/7521, chr1-CpG: 35/Downstream/28819

Upstream sequence

GTAAGGAGTTGGGGTGTATTTTCCCTTCTCCAGTGATCAGGAAGACCAAGAGGGTTTCCTGGGGTCTCAGTGTGACCTCATGCAAAGTCACTCTCTAGCA

Downstream sequence

CTGCTGCTGAATGAGGGGAGGAGAGGCATGGAAGAAAAAATATTCTTCCACTGCACTCTGAACAACTTCCATTACCAACCCGATGCAGGTCATGATGTTC