VISDB Viral Integration Site DataBase

VIS ID

TVIS10010131

Fusion event

HBV-KIAA1549L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1753

Orient

-

Integrated sequence

ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTC

Chromosome

chr11

Cytoband

p13

Reference genome

Start

End

33408383/33386837 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-93-3p ; hsa-mir-361-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6806-5p ; hsa-mir-3622b-5p ; hsa-mir-654-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-34b-3p ; hsa-mir-802 ; hsa-mir-7-2-3p ; hsa-mir-5688 ; hsa-mir-7-1-3p ; hsa-mir-495-3p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-4789-5p ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-1284 ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-4719 ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-6757-3p ; hsa-mir-5700 ; hsa-mir-6867-5p ; hsa-mir-138-2-3p ; hsa-mir-3650

Nearest miRNA

hsa-mir-210/Upstream/4909289; hsa-let-7a-2/Downstream/1555000;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/9889, chr11-CpG: 16/Downstream/271836

Nearby gene

HIPK3(-32444) ; KIAA1549L(+155494) ;

Upstream sequence

tcatgaggggtattggtctgtagttttgttttgctaaaaggtgtctggttttgttagaagggtagtgctggtctataaaataataggggccagatgcggt

Downstream sequence

ggctcaatcctgtaatcccaacactttgggagcccaaggagggtggatcacttgaggtcaggagttcgagaccatcctggttaatgtgatgaaaccccgt