VISDB Viral Integration Site DataBase

VIS ID

TVIS10010137

Fusion event

HBV-GYS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1801

Orient

-

Integrated sequence

GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG

Chromosome

chr12

Cytoband

p12.1

Reference genome

Start

End

21689706/21536772 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-6794-3p ; hsa-mir-4423-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/3863378; hsa-let-7i/Downstream/2675649;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/8724, chr12-CpG: 21/Downstream/120782

Upstream sequence

TTAAATTCACCATTTTAAAAACACTTTTCCGTCTTCTGCCTTTAATGAGTGCTCCTCCTCATGCCTAACTTTATGGGGGAAACAAGAGTTGGGGAAAATA

Downstream sequence

ACTTGGATCTTATCCTAAATTACAAAATTGTCATTCACTCAATTTCTTCCACTTTTTAGGCAGAGAATAAACTCCATTGTAATACTTAGAAGGAGAAAAT