VISDB Viral Integration Site DataBase

VIS ID

TVIS10010138

Fusion event

HBV-ITPR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1792

Orient

-

Integrated sequence

CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG

Chromosome

chr12

Cytoband

p11.23

Reference genome

Start

End

26945214/26792281 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-324-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-187-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6752-3p ; hsa-mir-4793-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/918202; hsa-let-7i/Downstream/15531419;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/596084, chr12-CpG: 101/Downstream/40268

Upstream sequence

TCTAAAAATTTGTCCTATTCCTTACACAAAAACATCTGTGAAAATCACTAAGGCAGTCATTTCATCCTGAAGACTTAAAGAATTGGAACTGAATTTGAAG

Downstream sequence

ATAATGGAAGGAAGGAAACGACAAGAAGAAGCAAGGAGTCTGAATCTGTTACAAGACATatatgatcactggcattaaaagtcaaacaggattttaatgg