VISDB Viral Integration Site DataBase

VIS ID

TVIS10010139

Fusion event

HBV-CCDC91 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

-

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr12

Cytoband

p11.22

Reference genome

Start

End

28603677/28450744 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5689

Nearest miRNA

hsa-mir-1244-3/Upstream/2576665; hsa-let-7i/Downstream/13872956;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/259770, chr12-CpG: 91/Downstream/698298

Upstream sequence

ACTTATTATAAAGAACATATATGTTGCAACACTAATATCCACCTGCTATTTGTTGCATCTAATTAGAGGTTGTGTGTGCATCTGTGTATCAAGGTAAGTA

Downstream sequence

ATTTTTAAAGCCAAGTTTAAAATAACTCATCTAAATCATGTATTCATAGATATAAAATATACACACACCAACAAATACACTTTTAACACTTACTTTTGAG