VISDB Viral Integration Site DataBase

VIS ID

TVIS10010145

Fusion event

HBV-STARD13 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1871

Orient

+

Integrated sequence

GTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGC| |CTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTC

Chromosome

chr13

Cytoband

q13.1

Reference genome

Start

End

33786108/33211971 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-122-5p ; hsa-mir-4452 ; hsa-mir-3658 ; hsa-mir-1231 ; hsa-mir-183-3p ; hsa-mir-516b-5p ; hsa-mir-4276 ; hsa-mir-4653-3p ; hsa-mir-219a-1-3p ; hsa-mir-570-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-148a-3p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4295 ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-2276/Upstream/9049467; hsa-mir-1267/Downstream/6452063;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/194681, chr13-CpG: 88/Downstream/137822

Nearest cancer related gene

STARD13(TSG, No orient, 0)

Upstream sequence

cttatgtatgtaaaatatacacatatgtctatacatacttgtacatatataCCCATGTTATACACCCATAAGAATTGCTTTTCACTGaaacagaatcata

Downstream sequence

atatatgtattattctcagacttactctgttcattggacaatatgtcttggagattTTCAAATAAACAAATAAGAAAGCTAATAACAAATTAGCTCAGTG