Basic Information
VIS ID
TVIS10010155
Fusion event
HBV-LOC101928462 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1789
Orient
-
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
81621883/81155539 (Hg38)
End
81621883/81155539 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101928462
Nearest miRNA
hsa-mir-1260a/Upstream/3889249; hsa-mir-1185-1/Downstream/12792687;
Nearest TSS
ENST00000550708/Upstream/12383; ENST00000618431/Downstream/14685;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/200322, chr14-CpG: 147/Downstream/64502
Nearby gene
TSHR(-9237) ; GTF2A1(+19913) ;
Upstream sequence
ctgcctcctcaccagctccactttaatatctaatagcaatctcaaaattaacatgtccaaaaccaaactcctaatcttctactccaaaacccacttcgtc
Downstream sequence
tactgccttctccatcttggtcaatggcaatacatccttcaaagtgctcagacaaaaaatcttgaagtcttccttgtttcttctctttctctcacactcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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