VISDB Viral Integration Site DataBase

VIS ID

TVIS10010175

Fusion event

HBV-C18orf25 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2140

Orient

+

Integrated sequence

CATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAG| |CGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGA

Chromosome

chr18

Cytoband

q21.1

Reference genome

Start

End

43762964/46182998 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-183-5p ; hsa-mir-221-5p ; hsa-mir-656-3p ; hsa-mir-3128 ; hsa-mir-4795-3p ; hsa-mir-8073 ; hsa-mir-142-3p ; hsa-mir-5589-3p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-3613-3p ; hsa-mir-5011-5p ; hsa-mir-570-3p ; hsa-mir-152-3p ; hsa-mir-222-3p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6514-3p ; hsa-mir-6894-3p ; hsa-mir-4799-5p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-126-5p ; hsa-mir-660-5p ; hsa-mir-1273d ; hsa-mir-500a-3p ; hsa-mir-767-5p ; hsa-mir-410-3p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-510-3p ; hsa-mir-4263 ; hsa-mir-5571-5p ; hsa-mir-708-3p ; hsa-mir-7844-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-3064-3p ; hsa-mir-155-3p ; hsa-mir-5581-3p ; hsa-mir-1283 ; hsa-mir-7853-5p ; hsa-mir-105-5p

Nearest miRNA

hsa-mir-1-2/Upstream/1212832; hsa-mir-122/Downstream/1197498;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/7860, chr18-CpG: 65/Downstream/150384

Upstream sequence

GGTGGTTGCAATCTCACAATTTATATTTAAGTTCCGGGTAGGCCAAATTCAGTGCATTATGGACAGATCCATTCAGCTGTATTAATATTAGAGTTCCCTT

Downstream sequence

TCTGTACTCTAACTTTTTAGCACTCCAGTTTCCCAGTCAGCTTCACTGTTGAAGGAAAGAAAACCGAAAAACttaccacactaaaaaaaaaaaggaagag