VISDB Viral Integration Site DataBase

VIS ID

TVIS10010180

Fusion event

HBV-RANBP3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1793

Orient

-

Integrated sequence

GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

5925629/5925618 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-455-3p ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-1227/Upstream/992878; hsa-let-7e/Downstream/464020;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/10328, chr19-CpG: 145/Downstream/51811

Upstream sequence

AACCTGGATTCTGGGCCTGAGTCGGGCACGGGGACCACAGACCCCTCTCTGGCAGAAGCCCTCGCGGCCACCTGCATCGCCATGCCAGGCTGGCCGCTGA

Downstream sequence

CACCGAGACACACACCTGGAACTGATATACTGGAGGAAATAGTTCGTTGCGGTTGGCGTGTCTGCGCTGGGGTGTCCAGCATTCTCCATGTCGGCTTCGT