VISDB Viral Integration Site DataBase

VIS ID

TVIS10010187

Fusion event

HBV-NUP35 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1753

Orient

-

Integrated sequence

ACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAG| |ATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTC

Chromosome

chr2

Cytoband

q32.1

Reference genome

Start

End

184003365/183138637 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-6868-3p ; hsa-mir-4477a ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-5007-5p ; hsa-mir-7703 ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4793-3p ; hsa-mir-1205 ; hsa-mir-3925-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-1273g-3p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-508-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p

Nearest miRNA

hsa-mir-10b/Upstream/1832985; hsa-mir-1244-1/Downstream/1240338;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/100084, chr2-CpG: 26/Downstream/121978

Upstream sequence

TAGGAAATCTGGATTAAAGAATATAAGAAACTCTTAGTCATGGTATATTACTGCCCCTGGTAAAGAACATTGAATGTGTTTTTTCTACTTTCCCCATCCT

Downstream sequence

CATCCCTGAATATTTTTTTCTGCTGCAATTTAAGTTTTCTTCTGCTTTTCTTCTTCCTTTATATTTTTTATTACTTTTTTTCTTGAGAAGTTCTTTCACT