Basic Information
VIS ID
TVIS10010199
Fusion event
HBV-LOC105374457 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1731
Orient
-
Integrated sequence
ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
34531760/34306693 (Hg38)
End
34531760/34306693 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374457
Nearest miRNA
hsa-mir-1301/Upstream/888129; hsa-mir-10b/Downstream/1164712;
Nearest TSS
ENST00000437798/Upstream/239467; ENST00000422558/Downstream/77095;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/579076, chr2-CpG: 191/Downstream/2048561
Nearby gene
MYADML(-578476) ;
Upstream sequence
tatccttccctaaaagacctaccactatttactttgaaaaccatacatagagaaaaaaggactaattggccagttcaagggttattggatagagtctaag
Downstream sequence
ttgactctgatactgagggacccagagcaccctcatcgaggctcccctgataaagcaggcatagatgagtcagctagtatacttattgcccatgcttgtc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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