Basic Information
VIS ID
TVIS10010204
Fusion event
HBV-chr20 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2333
Orient
+
Integrated sequence
GAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCC| |GGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAA
Host Sequence
Chromosome
chr20
Cytoband
q12
Reference genome
End
38261441/39632799 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1116167; hsa-mir-1-1/Downstream/1536224;
Nearby gene
LINC01734(-408050) ; MAFB(+1053076) ;
Nearest cancer related gene
MAFB(OG, +1053076) ;
Upstream sequence
CAGAAGTCCTAGGACACTGGTATCCttgtgttcagggttagtatccacagtacaagtggcacagagaaactgaaatctccaaaggcaggttactggagaa
Downstream sequence
gaaaagaaatgctaagccataacacacatgagaaaatcttggaggaatcaggatggctccttctggagatctttaccagctaattatccagagtgcttcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate