VISDB Viral Integration Site DataBase

VIS ID

TVIS10010205

Fusion event

HBV-STAU1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1926

Orient

+

Integrated sequence

TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA| |TTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCT

Chromosome

chr20

Cytoband

q13.13

Reference genome

Start

End

47773746/49157209 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-27a-3p ; hsa-mir-16-5p ; hsa-mir-877-5p ; hsa-mir-30e-5p ; hsa-mir-5011-5p ; hsa-mir-218-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-222-5p ; hsa-mir-190a-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-1290 ; hsa-mir-16-1-3p ; hsa-mir-4781-3p ; hsa-mir-218-2-3p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-103a-2/Upstream/1990151; hsa-mir-1-1/Downstream/706650;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/110297, chr20-CpG: 83/Downstream/30607

Upstream sequence

caagtgatccacctgcctcagtctcccaaagtgctgggattacaggcatgacccaccacgtccagccTCAAAATTCTCTTCCAATTACTTCTCATGAAAG

Downstream sequence

ATATTTTGCAAACTTGATTTAAACACACAGCAGTACTTCACACAAATTAAGACAATGTTTGTTTTGATGCTGCAATGTGTTTGTGGGCTCTTGTTTGAAA