VISDB Viral Integration Site DataBase

VIS ID

TVIS10010214

Fusion event

HBV-chr3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1731

Orient

-

Integrated sequence

ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC

Chromosome

chr3

Cytoband

q13.2

Reference genome

Start

End

111543891/111825044 (Hg38)

Orient

-

Location type

Intronic

Target gene

PHLDB2 ; PLCXD2

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1-3p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-92a-3p ; hsa-mir-432-5p ; hsa-mir-376a-5p ; hsa-mir-382-3p ; hsa-mir-1273e ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-503-3p ; hsa-mir-6861-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4291 ; hsa-mir-193a-5p ; hsa-mir-205-5p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-29c-3p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-202-5p ; hsa-mir-298 ; hsa-mir-4709-3p

Nearest miRNA

hsa-let-7g/Upstream/2222147; hsa-mir-12124/Downstream/287757;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/150347, chr3-CpG: 59/Downstream/34346

Upstream sequence

acatagagagaccctgtcactacaaaaaaaaaaattaattagcaggtcatggtggcacatctgtggtcccagctatttgggaggctgaggcaggaggacc

Downstream sequence

CATGGTAAACCCCTGAGAAGAAATTTTTGTGCTTTTAGCATGCTCACCATTTACAGGTAAGAAGACAAAAATACTGAGAAGAAAAAGATTTGCTCAAACC