VISDB Viral Integration Site DataBase

VIS ID

TVIS10010215

Fusion event

HBV-STXBP5L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2252

Orient

+

Integrated sequence

TAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGA| |GTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGA

Chromosome

chr3

Cytoband

q13.33

Reference genome

Start

End

121117759/121398912 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6083 ; hsa-mir-3692-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-5579-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-374c-3p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-1263 ; hsa-mir-150-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-660-3p ; hsa-mir-5193

Nearest miRNA

hsa-let-7g/Upstream/349197; hsa-mir-12124/Downstream/1762882;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/490193, chr3-CpG: 41/Downstream/146710

Upstream sequence

tgaaattgaggcagtagttaatagcctaccaaccaaaaaaagcccaggaccagatggatacacagccaaattctaccagaggtacaaagaggagctagta

Downstream sequence

ctgaatagaactaagagtggtcgctcgaggcactgctcgaacagacactggggcaactacttttcacccagtgtcctccggaaaagaaagatctggaggg