VISDB Viral Integration Site DataBase

VIS ID

TVIS10010216

Fusion event

HBV-CPNE4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1810

Orient

-

Integrated sequence

CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT

Chromosome

chr3

Cytoband

q22.1

Reference genome

Start

End

131369368/131650524 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-122-5p

Nearest miRNA

hsa-let-7g/Upstream/2378281; hsa-mir-1224/Downstream/335331;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/123347, chr3-CpG: 25/Downstream/384512

Upstream sequence

aaaaaaaaaacaaaCTTTTTACAAGTTTTTAAATTTCTAAAAAAATATAGACCAGggccaggtgcagtggctcatgcctgtaatcccagcactttgggat

Downstream sequence

aggcgggtggatcacaaggtcgggagatcgagaccacggtgaaaccccgtctctactaaaaatacaaaaaattagccgggcgtggtggtgggcgcctgta