VISDB Viral Integration Site DataBase

VIS ID

TVIS10010218

Fusion event

HBV-CLSTN2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1777

Orient

-

Integrated sequence

AGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTA| |GGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAA

Chromosome

chr3

Cytoband

q23

Reference genome

Start

End

140259985/140541143 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-3180-5p ; hsa-mir-3607-3p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-10b-3p ; hsa-mir-1343-5p ; hsa-mir-145-3p ; hsa-mir-1914-5p ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-5703 ; hsa-mir-6763-5p ; hsa-mir-6825-5p ; hsa-mir-6878-5p ; hsa-mir-7152-5p ; hsa-mir-939-5p

Nearest miRNA

hsa-let-7g/Upstream/6103237; hsa-mir-1224/Downstream/11024733;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/604870, chr3-CpG: 37/Downstream/141474

Upstream sequence

AGAAGTATTTGAAGCAAATATACTGAGATTACAACTTTCCTTCCAGTTGAAGGATGACATCAGCAGCTTTATAGTGGAAACACTTTAACTTCTCAGGAAT

Downstream sequence

TGGCATGTAGGCCAAAGGCTTGGaagcaagcttaggagtttgaatcttggcttcactcacttctggttatgtggctttggtcaagttacctaacttTGAA