Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010230
Fusion event
HBV-ANXA10 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1824
Orient
-
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
End
169092613/168171462 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/2785125; hsa-mir-1305/Downstream/3014722;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/2297273, chr4-CpG: 27/Downstream/146936
Upstream sequence
ccattccactcgggtggattccactccattccattccattccattccattccattccatttcattccattcccctcgggttgattccagtccgttccttt
Downstream sequence
AGGAAAGATGACCCATGGTTTTCATATTTTTAACATCACTAAAATTCAGACACACCCATTTTTTTTGAATTAATAGAGACTGGGGTAATTGGAGCATAGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.