VISDB Viral Integration Site DataBase

VIS ID

TVIS10010254

Fusion event

HBV-ARHGAP18 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1801

Orient

-

Integrated sequence

GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG

Chromosome

chr6

Cytoband

q22.33

Reference genome

Start

End

129938722/129617577 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-4725-5p ; hsa-mir-4696 ; hsa-mir-570-3p ; hsa-mir-5699-3p ; hsa-mir-520f-5p ; hsa-mir-4421 ; hsa-mir-6501-3p ; hsa-mir-339-5p ; hsa-mir-451b ; hsa-mir-10b-5p ; hsa-mir-3667-5p ; hsa-mir-10a-5p ; hsa-mir-4282 ; hsa-mir-6759-5p ; hsa-mir-6796-5p ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-15b-3p ; hsa-mir-581 ; hsa-mir-5187-3p ; hsa-mir-2681-3p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-486-3p

Nearest miRNA

hsa-mir-10398/Upstream/3132864; hsa-mir-1202/Downstream/2174595;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/687403, chr6-CpG: 208/Downstream/401464

Upstream sequence

ttttttatttttggagacagagtctcactctgttacccaggctggagtgcagtggcacaatctcagcccactgcaacctctgcctcctgggttcaagcag

Downstream sequence

TAGCCTTGATATAAACAACTTAACGTTTCTTTGCCAGGATGCAATTCTAAAACATAAGAATTAAAAAAAAAAACTCTTAGCCACTTTAAAAATCTTGGGC