Basic Information
VIS ID
TVIS10010256
Fusion event
HBV-LOC105378035 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1781
Orient
-
Integrated sequence
ATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAG| |GCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTG
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
143846469/143525332 (Hg38)
End
143846469/143525332 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378035
Nearest miRNA
hsa-mir-10398/Upstream/2841449; hsa-mir-1202/Downstream/7577343;
Nearest TSS
ENST00000381078/Upstream/13642; ENST00000545919/Downstream/11513;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/13526, chr6-CpG: 126/Downstream/11274
Nearby gene
FUCA2(-13449) ; PHACTR2-AS1(+28998) ;
Upstream sequence
tccctctgttgcccaggctggagtgcagtggcacaatctcggttcactgcaacctccctctcctgggttcaagtgattctcctccctcagcctcccgagc
Downstream sequence
atgaggcttgagcaaatgaggccagttgtacaagttcagtgtcagatcctatttaaagttttgatattttgttcatcatgtttatttttttcattaattc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate