VISDB Viral Integration Site DataBase

VIS ID

TVIS10010261

Fusion event

HBV-MYO6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1819

Orient

+

Integrated sequence

TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA

Chromosome

chr6

Cytoband

q14.1

Reference genome

Start

End

76619879/75910162 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-22-3p ; hsa-mir-140-5p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-155-3p ; hsa-mir-4719 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-382-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-1264 ; hsa-mir-3692-3p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10398/Upstream/481689; hsa-mir-10524/Downstream/2629101;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/160612, chr6-CpG: 132/Downstream/1552352

Upstream sequence

ttcacgccattctcctgcctcagcctccagagtagctgggactacatgcgcccgccaccacgcccggctaattttttatatttttagtagagaagaggtt

Downstream sequence

AGCTGTTCACTGTCTGTGTAGTGAGTTCTGACCACAGATTACCTTTGTTTTGCAAAAAATGACAGTGAGCTGTTCTTTTTAGCTGTAAATATTATAATTA