Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010263
Fusion event
HBV-SNX14 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2395
Orient
+
Integrated sequence
TATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCA| |GACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTT
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
Start
End
86258864/85549146 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/7009837; hsa-mir-1202/Downstream/4763596;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/98469, chr6-CpG: 107/Downstream/44249
Upstream sequence
atatttaatgtgtacaatttgacatatttggacatatacatatacccataaaaccattacaacaatcgagataatgagtacatcacccccagtagattct
Downstream sequence
ATAAAAATTTTAAACAAAAAGTAGTATTTAAAGTACATCACTTTAAATATCACTAAAAATAAGCCATGGTTACTCCTCTAAGGGTTATTAGGGTAAGAGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.