Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10010265
Fusion event
HBV-FAM71F1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr7
Cytoband
q32.1
Reference genome
End
128371459/128731405 (Hg38)
Orient
-
Location type
UTR3
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/523462; hsa-mir-10399/Downstream/1038978;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/199088, chr7-CpG: 61/Downstream/7655
Upstream sequence
aggatattggtctaaaattctcttttttggttgtgtctctgccaggctttggtatcagggtgatgcgggcctcataggatacccaggaattgaactcagc
Downstream sequence
AGAGAAGTGGAAGGAAGCAAAATGGAGGTGATGAGAAAGGTGGTGGGAGAAAGTCAGCAGATGAGAGACACAAAGAGAAGTGGTAATAGGAAACGGAAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.