VISDB Viral Integration Site DataBase

VIS ID

TVIS10010271

Fusion event

HBV-RSBN1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2012

Orient

+

Integrated sequence

ACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCT| |GTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACC

Chromosome

chr7

Cytoband

q11.23

Reference genome

Start

End

77336056/77706739 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-4772-3p ; hsa-mir-6083 ; hsa-mir-2053 ; hsa-mir-190a-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-569 ; hsa-mir-5011-5p ; hsa-mir-513b-3p ; hsa-mir-1277-5p ; hsa-mir-6736-3p ; hsa-mir-6504-3p ; hsa-mir-4279 ; hsa-mir-6749-3p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-4284 ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6890-3p ; hsa-mir-1303 ; hsa-mir-6848-3p ; hsa-mir-5096 ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-4256 ; hsa-mir-197-3p ; hsa-mir-193b-5p ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4716-5p ; hsa-mir-4494 ; hsa-mir-4781-3p ; hsa-mir-4463 ; hsa-mir-483-5p ; hsa-mir-377-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-5580-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-181a-2-3p ; hsa-mir-4537 ; hsa-mir-4539 ; hsa-mir-4680-5p ; hsa-mir-4724-5p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-455-3p ; hsa-mir-4740-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6511a-5p ; hsa-mir-6516-5p

Nearest miRNA

hsa-mir-10525/Upstream/1791470; hsa-mir-10399/Downstream/14497276;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/9555, chr7-CpG: 139/Downstream/91275

Upstream sequence

tctttttaaaaattttcgtggtgtccctagaatgtagtccatctaaattgaaatctatttcaaataacattccactcacatcacatgtgctccaaggacc

Downstream sequence

ACTCTTTTATTGAATTCTTAATTCACCATAGTTTGAATTTTGGAAGGCCACTTGCACAGTGCTTGTAGATAAAGATTGATTGTAGTAGGGCAATTACAGT