VISDB Viral Integration Site DataBase

VIS ID

TVIS10010283

Fusion event

HBV-ANK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1820

Orient

-

Integrated sequence

TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

41701703/41844185 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-513b-5p ; hsa-mir-597-5p ; hsa-mir-6747-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-1-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-4802-5p ; hsa-mir-6732-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-663b ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-7106-5p ; hsa-mir-6825-5p ; hsa-mir-874-5p ; hsa-mir-6894-5p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-3605-5p ; hsa-mir-1204 ; hsa-mir-1247-3p ; hsa-mir-5587-3p ; hsa-mir-6840-5p ; hsa-mir-2392 ; hsa-mir-1273e ; hsa-mir-4709-3p ; hsa-mir-4684-5p ; hsa-mir-4635 ; hsa-mir-942-5p ; hsa-mir-877-3p ; hsa-mir-376c-3p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-202-3p

Nearest miRNA

hsa-mir-124-1/Upstream/183677; hsa-mir-10400/Downstream/1052012;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/15029, chr8-CpG: 39/Downstream/31840

Upstream sequence

ttgcctcctgggtcctaatgcctgtcagacaaacttcctcccgcctctcttctctgaggctagtcctgcttctaaaaaccactccctgtctctggtgctt

Downstream sequence

TGAGAGGAGGGCATCTGTGCCCTGCCCTGGTCCAGCTCCTCACCTTGGCAGATCTTGGTATCCCCTCGGGGAAGTCTATAGATGAACCATGGGTGCGACC