Basic Information
VIS ID
TVIS10010284
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1827
Orient
-
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
End
50623579/49711019 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/6814744; hsa-mir-10400/Downstream/12003769;
Nearby gene
PPDPFL(-634937) ; SNTG1(+201018) ;
Upstream sequence
agccagaagcattctaagaaacatcttagggatgtgtacattcaagtcacagagttgaacattcccctttctcagagcaggtttgaaacaatcttctcgt
Downstream sequence
tgaaaaaagcaaacaatgggaaaagggttccttattcaataaatggtgctggtataactggctagcaatatgaagaagattgaaacccgaccccttcatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate