VISDB Viral Integration Site DataBase

VIS ID

TVIS10010295

Fusion event

HBV-SCAI integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1842

Orient

+

Integrated sequence

TGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATC| |ATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGG

Chromosome

chr9

Cytoband

q33.3

Reference genome

Start

End

127764564/125002285 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1273e ; hsa-mir-6771-5p ; hsa-mir-873-5p ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-302f ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4758-3p ; hsa-mir-4537 ; hsa-mir-4286 ; hsa-mir-3651 ; hsa-mir-6769a-3p ; hsa-mir-3943 ; hsa-mir-4323 ; hsa-mir-625-5p ; hsa-mir-129-5p ; hsa-mir-3149 ; hsa-mir-411-5p

Nearest miRNA

hsa-let-7a-1/Upstream/308487; hsa-mir-12126/Downstream/2688402;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/60750, chr9-CpG: 70/Downstream/140748

Upstream sequence

tggagaccaacctggctaacacggtgaaaccccgtctctactaaatatatataaaaaaaaaattagccgggcatggtggcaggtgcctgtagtcccagct

Downstream sequence

AGAATATTCTCCGAAAACTTGAATGGAGAAGTAAAGATCCTGACTACATGGCTACAAGACAAAGTCCCTTCTGTGGCTTTCTCTACATAGACTTTGGGAA